Hermann Schätzl Comparative Biology and Experimental Medicine, University of Calgary, Canada
2 protocols

Yuzuru Taguchi
  • Comparative Biology and Experimental Medicine, University of Calgary, Canada
  • 2 Author merit


M.D.  School of Medicine, Tohoku University, Japan in 1996
Ph.D., Graduate School of Medicine, Tohoku University, Japan, 2003

Current position

Research Associate, Department of Comparative Biology & Experimental Medicine, Faculty of Veterinary Medicine, University of Calgary, Alberta, Canada


  1. Taguchi, Y. and Schätzl, H. M. (2013). Identifying critical sites of PrPc-PrPSc interaction in prion-infected cells by dominant-negative inhibition. Prion 7(6): e1003466--1003461.
  2. Taguchi, Y., Mistica, A. M., Kitamoto, T. and Schätzl, H. M. (2013). Critical significance of the region between Helix 1 and 2 for efficient dominant-negative inhibition by conversion-incompetent prion protein. PLoS Pathog 9(6): e1003466.
  3. Taguchi, Y., Hohsfield, L. A., Hollister, J. R. and Baron, G. S. (2013). Effects of FlAsH/tetracysteine (TC) Tag on PrP proteolysis and PrPres formation by TC-scanning. Chembiochem 14(13): 1597-1610, 1510.
  4. Gilch, S., Chitoor, N., Taguchi, Y., Stuart, M., Jewell, J. E. and Schätzl, H. M. (2011). Chronic wasting disease. Top Curr Chem 305: 51-77.
  5. Taguchi, Y., Shi, Z. D., Ruddy, B., Dorward, D. W., Greene, L. and Baron, G. S. (2009). Specific biarsenical labeling of cell surface proteins allows fluorescent- and biotin-tagging of amyloid precursor protein and prion proteins. Mol Biol Cell 20(1): 233-244.
  6. Taguchi, Y., Mohri, S., Ironside, J. W., Muramoto, T. and Kitamoto, T. (2003). Humanized knock-in mice expressing chimeric prion protein showed varied susceptibility to different human prions. Am J Pathol 163(6): 2585-2593.
  7. Shiga, Y., Taguchi, Y. and Jin, K. (2003). Homozygous Prion Protein Genotype at Codon 129 Is Not a Predisposing Factor for Developing Familial Creutzfeldt–Jakob Disease with a Point Mutation of Val to Ile at Codon 180. Ann Neurol. 54: S69-S69.
  8. Tateyama, M., Saito, N., Fujihara, K., Shiga, Y., Takeda, A., Narikawa, K., Hasegawa, T., Taguchi, Y., Sakuma, R., Onodera, Y., Ohnuma, A., Tobita, M. and Itoyama, Y. (2003). Familial inclusion body myositis: a report on two Japanese sisters. Intern Med 42(10): 1035-1038.
  9. Hirayama, K., Taguchi, Y., Sato, M. and Tsukamoto, T. (2003). Limbic encephalitis presenting with topographical disorientation and amnesia. J Neurol Neurosurg Psychiatry 74(1): 110-112.
2 Protocols published
Small-scale Triton X-114 Extraction of Hydrophobic Proteins
Authors:  Yuzuru Taguchi and Hermann M. Schätzl, date: 06/05/2014, view: 6742, Q&A: 0
Here we introduce a protocol for Triton X-114 extraction which we used in our recently-published paper (Taguchi et al., 2013). It is a versatile method to concentrate or partially purify hydrophobic proteins. The presented protocol is based ...
Small-scale Subcellular Fractionation with Sucrose Step Gradient
Authors:  Yuzuru Taguchi and Hermann M. Schätzl, date: 06/05/2014, view: 5767, Q&A: 0
Here, we introduce the protocol for small-scale and simple subcellular fractionation used in our recent publication (Taguchi et al., 2013), which uses homogenization by passing through needles and sucrose step-gradient.
Subcellular ...