Search

Javier G. Magadán
  • Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, USA
Contributions
  • 2 Author merit

Education

Ph.D. in Cell Biology, Universidad de Buenos Aires, Argentina

Current position

Staff Scientist, NIAID, National Institutes of Health, USA

Publications

  1. Magadan, J. G., Khurana, S., Das, S. R., Frank, G. M., Stevens, J., Golding, H., Bennink, J. R. and Yewdell, J. W. (2013). Influenza A virus hemagglutinin trimerization completes monomer folding and antigenicity. J Virol 87(17): 9742-9753.
  2. Mardones, G. A., Burgos, P. V., Lin, Y., Kloer, D. P., Magadan, J. G., Hurley, J. H. and Bonifacino, J. S. (2013). Structural basis for the recognition of tyrosine-based sorting signals by the mu3A subunit of the AP-3 adaptor complex. J Biol Chem 288(13): 9563-9571.
  3. Hickman, H. D., Reynoso, G. V., Ngudiankama, B. F., Rubin, E. J., Magadan, J. G., Cush, S. S., Gibbs, J., Molon, B., Bronte, V., Bennink, J. R. and Yewdell, J. W. (2013). Anatomically restricted synergistic antiviral activities of innate and adaptive immune cells in the skin. Cell Host Microbe 13(2): 155-168.
  4. Han, Y., David, A., Liu, B., Magadan, J. G., Bennink, J. R., Yewdell, J. W. and Qian, S. B. (2012). Monitoring cotranslational protein folding in mammalian cells at codon resolution. Proc Natl Acad Sci U S A 109(31): 12467-12472.
  5. Prabhu, Y., Burgos, P. V., Schindler, C., Farias, G. G., Magadan, J. G. and Bonifacino, J. S. (2012). Adaptor protein 2-mediated endocytosis of the beta-secretase BACE1 is dispensable for amyloid precursor protein processing. Mol Biol Cell 23(12): 2339-2351.
  6. Magadan, J. G. and Bonifacino, J. S. (2012). Transmembrane domain determinants of CD4 Downregulation by HIV-1 Vpu. J Virol 86(2): 757-772.
  7. Arenas, G. N., Grilli, D. J., Samartino, L. E., Magadan, J. and Mayorga, L. S. (2010). Brucella alters endocytic pathway in J774 macrophages. Virulence 1(5): 376-385.
  8. Perez-Victoria, F. J., Schindler, C., Magadan, J. G., Mardones, G. A., Delevoye, C., Romao, M., Raposo, G. and Bonifacino, J. S. (2010). Ang2/fat-free is a conserved subunit of the Golgi-associated retrograde protein complex. Mol Biol Cell 21(19): 3386-3395.
  9. Perez-Victoria, F. J., Abascal-Palacios, G., Tascon, I., Kajava, A., Magadan, J. G., Pioro, E. P., Bonifacino, J. S. and Hierro, A. (2010). Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex. Proc Natl Acad Sci U S A 107(29): 12860-12865.
  10. Magadan, J. G., Perez-Victoria, F. J., Sougrat, R., Ye, Y., Strebel, K. and Bonifacino, J. S. (2010). Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps. PLoS Pathog 6(4): e1000869.
  11. Magadan, J. G., Barbieri, M. A., Mesa, R., Stahl, P. D. and Mayorga, L. S. (2006). Rab22a regulates the sorting of transferrin to recycling endosomes. Mol Cell Biol 26(7): 2595-2614.
  12. Mesa, R., Magadan, J., Barbieri, A., Lopez, C., Stahl, P. D. and Mayorga, L. S. (2005). Overexpression of Rab22a hampers the transport between endosomes and the Golgi apparatus. Exp Cell Res 304(2): 339-353.

2 Protocols published
Radioactive Pulse-Chase Analysis and Immunoprecipitation
Author:  Javier G. Magadán, date: 04/20/2014, view: 4376, Q&A: 0
Labeling of newly-synthesized polypeptides with radioactive amino acids followed by immunoprecipitation allows quantitative analysis of the fate of a given protein in a time-dependent manner. This biochemical approach is usually used to study a ...
Zonal Sedimentation Analysis on Sucrose Gradients
Author:  Javier G. Magadán, date: 04/20/2014, view: 3328, Q&A: 0
Zonal sedimentation analysis on sucrose gradients allows estimation of the molecular size of an individual protein or a protein complex by centrifugation at a constant speed under nondenaturing conditions. This method is particularly suitable for ...