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Coauthors
Kyu-Ho Lee Department of Life Science and Interdisciplinary Program of Integrated Biotechnology, Sogang University, South Korea
1 protocol

Soon-Jung Park Department of Environmental Medical Biology and Institute of Tropical Medicine, Yonsei University College of Medicine, South Korea
1 protocol

Mi-Ae Lee Department of Life Science and Interdisciplinary Program of Integrated Biotechnology, Sogang University, South Korea
1 protocol

Jeong-A Kim Department of Life Science and Interdisciplinary Program of Integrated Biotechnology, Sogang University, South Korea
1 protocol

Hyun-Jung Lee
  • National Cancer Institute, National Institutes of Health, USA
Contributions
  • 1 Author merit

Education

Ph.D. in Environmental Science, Department of Environmental Science, Hankuk University of Foreign Studies in South Korea, 2008

Current Position

Post-doctoral Fellow, Biochemical Genetics Section, Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes o Health, Bethesda, MD, USA

Publications

  1. Moon, K., Six, D. A., Lee, H. J., Raetz, C. R. and Gottesman, S. (2013). Complex transcriptional and post-transcriptional regulation of an enzyme for lipopolysaccharide modification. Mol Microbiol 89(1): 52-64.
  2. Lee, H. J., Kim, J. A., Lee, M. A., Park, S. J. and Lee, K. H. (2013). Regulation of haemolysin (VvhA) production by ferric uptake regulator (Fur) in Vibrio vulnificus: repression of vvhA transcription by Fur and proteolysis of VvhA by Fur-repressive exoproteases. Mol Microbiol 88(4): 813-826.
  3. Kim, H. J., Lee, H. J., Lee, K. H. and Cho, J. C. (2012). Simultaneous Detection of Pathogenic Vibrio Species Using Multiplex Real-Time PCR. Food Control 23 (2): 491-498.
  4. Lee, H. J. and Lee, K. H. (2012). Identification of the fur-binding site in regulatory region of the vulnibactin-receptor gene in Vibrio vulnificus. J Microbiol Biotechnol 22(1): 46-49.
  5. Lee, K. J., Jeong, C. S., An, Y. J., Lee, H. J., Park, S. J., Seok, Y. J., Kim, P., Lee, J. H., Lee, K. H.* and Cha, S. S.* (2011). FrsA functions as a cofactor-independent decarboxylase to control metabolic flux. Nat Chem Biol 7(7): 434-436.
  6. Kim, H. S., Kim, S. M., Lee, H. J., Park, S. J. and Lee, K. H. (2009). Expression of the cpdA gene, encoding a 3',5'-cyclic AMP (cAMP) phosphodiesterase, is positively regulated by the cAMP-cAMP receptor protein complex. J Bacteriol 191(3): 922-930.
  7. Lee, H. J., Park, S. J., Choi, S. H. and Lee, K. H. (2008). Vibrio vulnificus rpoS expression is repressed by direct binding of cAMP-cAMP receptor protein complex to its two promoter regions. J Biol Chem 283(45): 30438-30450.
  8. Lee, H. J., Bang, S. H., Lee, K. H. and Park, S. J. (2007). Positive regulation of fur gene expression via direct interaction of fur in a pathogenic bacterium, Vibrio vulnificus. J Bacteriol 189(7): 2629-2636.
  9. Roh, J. B., Lee, M. A., Lee, H. J., Kim, S. M., Cho, Y., Kim, Y. J., Seok, Y. J., Park, S. J. and Lee, K. H. (2006). Transcriptional regulatory cascade for elastase production in Vibrio vulnificus: LuxO activates luxT expression and LuxT represses smcR expression. J Biol Chem 281(46): 34775-34784.
  10. Goo, S. Y., Lee, H. J., Kim, W. H., Han, K. L., Park, D. K., Kim, S. M., Kim, K. S., Lee, K. H. and Park, S. J. (2006). Identification of OmpU of Vibrio vulnificus as a fibronectin-binding protein and its role in bacterial pathogenesis. Infect Immun 74(10): 5586-5594.
  11. Park, K. J., Kang, M. J., Kim, S. H., Lee, H. J., Lim, J. K., Choi, S. H., Park, S. J. and Lee, K. H. (2004). Isolation and characterization of rpoS from a pathogenic bacterium, Vibrio vulnificus: role of sigmaS in survival of exponential-phase cells under oxidative stress. J Bacteriol 186(11): 3304-3312.
  12. Lee, H. J., Park, K. J., Lee, A. Y., Park, S. G., Park, B. C., Lee, K. H. and Park, S. J. (2003). Regulation of fur expression by RpoS and fur in Vibrio vulnificus. J Bacteriol 185(19): 5891-5896.
1 Protocol published
Measurement of Haemolysin Activities in Vibrio vulnificus
Authors:  Hyun-Jung Lee, Jeong-A Kim, Mi-Ae Lee, Soon-Jung Park and Kyu-Ho Lee, date: 03/05/2014, view: 2761, Q&A: 0
VvhA produced by Vibrio vulnificus exhibits cytolytic activity to human cells including erythrocytes. Since haemolysis by VvhA may provide iron for bacterial growth and pathogenicity, we investigated the expression of VvhA to elucidate the ...