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Reviewer
Pearl A. Campbell
  • Ottawa Hospital Research Institute
Research focus
  • Stem cell
  • 2 Author merit

Education

Ph.D. in Cellular and Molecular Medicine, Department of Cellular and Molecular Medicine, University of Ottawa, 2012

Current position

Director, StemCore Laboratories, Ottawa Hospital Research Institute, Ottawa, Canada

Publications

  1. Campbell, P. A. and Rudnicki, M. A. (2013). Oct4 interaction with Hmgb2 regulates Akt signaling and pluripotency. Stem Cells 31(6): 1107-1120.
  2. Sandie, R., Porter, C. J., Palidwor, G. A., Price, F., Krzyzanowski, P. M., Muro, E. M., Hoersch, S., Smith, M., Campbell, P. A. and Perez-Iratxeta, C. (2012). Paired SAGE-microarray Expression Data Sets Reveal Antisense Transcripts Differentially Expressed in Embryonic Stem Cell Differentiation. Computational Biology of Embryonic Stem Cells: 193.
  3. Campbell, P. A., Perez-Iratxeta, C., Andrade-Navarro, M. A. and Rudnicki, M. A. (2007). Oct4 targets regulatory nodes to modulate stem cell function. PLoS One 2(6): e553.
  4. Hailesellasse Sene, K., Porter, C. J., Palidwor, G., Perez-Iratxeta, C., Muro, E. M., Campbell, P. A., Rudnicki, M. A. and Andrade-Navarro, M. A. (2007). Gene function in early mouse embryonic stem cell differentiation. BMC Genomics 8: 85.
  5. Rolf, P., Bourbeau, M., Campbell, P., Seguin, I., Chauhan, B. M., Foster, B. C. and Cameron, D. W. (2006). Time‐Dependent Interaction Between Lopinavir/Ritonavir and Fexofenadine. The Journal of Clinical Pharmacology 46(7): 758-767.
  6. Perez-Iratxeta, C., Palidwor, G., Porter, C. J., Sanche, N. A., Huska, M. R., Suomela, B. P., Muro, E. M., Krzyzanowski, P. M., Hughes, E., Campbell, P. A., Rudnicki, M. A. and Andrade, M. A. (2005). Study of stem cell function using microarray experiments. FEBS Lett 579(8): 1795-1801.
  7. David-Beabes, G. L., Overman, M. J., Petrofski, J. A., Campbell, P. A., de Marzo, A. M. and Nelson, W. G. (2000). Doxorubicin-resistant variants of human prostate cancer cell lines DU 145, PC-3, PPC-1, and TSU-PR1: characterization of biochemical determinants of antineoplastic drug sensitivity. Int J Oncol 17(6): 1077-1086.
  8. Nucci, M. R., Robinson, C. R., Longo, P., Campbell, P. and Hamilton, S. R. (1997). Phenotypic and genotypic characteristics of aberrant crypt foci in human colorectal mucosa. Hum Pathol 28(12): 1396-1407.
  9. Carducci, M. A., Nelson, J. B., Chan-Tack, K. M., Ayyagari, S. R., Sweatt, W. H., Campbell, P. A., Nelson, W. G. and Simons, J. W. (1996). Phenylbutyrate induces apoptosis in human prostate cancer and is more potent than phenylacetate. Clin Cancer Res 2(2): 379-387.
  10. Lee, W. H., Morton, R. A., Epstein, J. I., Brooks, J. D., Campbell, P. A., Bova, G. S., Hsieh, W. S., Isaacs, W. B. and Nelson, W. G. (1994). Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis. Proc Natl Acad Sci U S A 91(24): 11733-11737.
  11. Sidransky, D., Von Eschenbach, A., Tsai, Y. C., Jones, P., Summerhayes, I., Marshall, F., Paul, M., Green, P., Hamilton, S. R., Frost, P. and et al. (1991). Identification of p53 gene mutations in bladder cancers and urine samples. Science 252(5006): 706-709.
  12. Giardiello, F. M., Hamilton, S. R., Kern, S. E., Offerhaus, G. J., Green, P. A., Celano, P., Krush, A. J. and Booker, S. V. (1991). Colorectal neoplasia in juvenile polyposis or juvenile polyps. Arch Dis Child 66(8): 971-975.
  13. Giardiello, F. M., Krush, A. J., Booker, S. V., Celano, P., Cox, D., Hamilton, S. R., Levin, S., Potter, K., Cross-Skinner, S., and Green, P. A. (1989). Familial Adenomatous Polyposis-a guide for patients and families. (The Johns Hopkins Cancer Information Service, The Johns Hopkins University Press)
2 Protocols published
Alkaline Phosphatase Staining
Author:  Pearl A. Campbell, date: 03/05/2014, view: 10196, Q&A: 0
Two main features characterize pluripotent cells; self-renewal (unlimited cell division) and the ability to give rise to all cells of the adult organism. Given the recent impact of induced pluripotent stem cells (iPSCs) and ongoing use of ...
IP-Kinase Assay
Author:  Pearl A. Campbell, date: 03/05/2014, view: 8504, Q&A: 0
Immunoprecipitation (IP)- Kinase assays are an invaluable tool to assess the activation status of intracellular signaling cascades within a specific cellular state and also to confirm the enzymatic activity of a specific kinase towards a putative ...