Search
Coauthors
Kevin Couper Department of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK
1 protocol

Eleanor Riley Department of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK
1 protocol

Christopher Hunter Department of Pathobiology, University of Pennsylvania, USA
1 protocol

Christiaan Saris Department of Inflammation Research, Amgen, Inc., USA
1 protocol

Ana Villegas-Mendez
  • Department of Immunology and Infection, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK
Contributions
  • 1 Author merit

Education

Ph.D. in Biochemistry, Imperial College London, UK

Current position

Faculty of Life Sciences, University of Manchester, Manchester, UK

Publications

  1. Villegas-Mendez, A., de Souza, J. B., Lavelle, S. W., Gwyer Findlay, E., Shaw, T. N., van Rooijen, N., Saris, C. J., Hunter, C. A., Riley, E. M. and Couper, K. N. (2013). IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals. PLoS Pathog 9(4): e1003293.
  2. Gwyer Findlay, E., Villegas-Mendez, A., de Souza, J. B., Inkson, C. A., Shaw, T. N., Saris, C. J., Hunter, C. A., Riley, E. M. and Couper, K. N. (2013). IL-27 receptor signaling regulates CD4+ T cell chemotactic responses during infection. J Immunol 190(9): 4553-4561.
  3. Villegas-Mendez, A., Fender, P., Garin, M. I., Rothe, R., Liguori, L., Marques, B. and Lenormand, J. L. (2012). Functional characterisation of the WW minimal domain for delivering therapeutic proteins by adenovirus dodecahedron. PLoS One 7(9): e45416.
  4. Villegas-Mendez, A., Greig, R., Shaw, T. N., de Souza, J. B., Gwyer Findlay, E., Stumhofer, J. S., Hafalla, J. C., Blount, D. G., Hunter, C. A., Riley, E. M. and Couper, K. N. (2012). IFN-gamma-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain. J Immunol 189(2): 968-979.
  5. Villegas-Mendez, A., de Souza, J. B., Murungi, L., Hafalla, J. C., Shaw, T. N., Greig, R., Riley, E. M. and Couper, K. N. (2011). Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection. J Immunol 187(6): 2885-2897.
  6. Rothe, R., Liguori, L., Villegas-Mendez, A., Marques, B., Grunwald, D., Drouet, E. and Lenormand, J. L. (2010). Characterization of the cell-penetrating properties of the Epstein-Barr virus ZEBRA trans-activator. J Biol Chem 285(26): 20224-20233.
  7. Villegas-Mendez, A., Garin, M. I., Pineda-Molina, E., Veratti, E., Bueren, J. A., Fender, P. and Lenormand, J. L. (2010). In vivo delivery of antigens by adenovirus dodecahedron induces cellular and humoral immune responses to elicit antitumor immunity. Mol Ther 18(5): 1046-1053.
  8. Liguori, L., Marques, B., Villegas-Mendez, A., Rothe, R. and Lenormand, J.-L. (2008). Liposomes-mediated delivery of pro-apoptotic therapeutic membrane proteins. Journal of Controlled Release 126(3): 217-227.
  9. Marques, B., Liguori, L., Paclet, M. H., Villegas-Mendez, A., Rothe, R., Morel, F. and Lenormand, J. L. (2007). Liposome-mediated cellular delivery of active gp91(phox). PLoS One 2(9): e856.
  10. Villegas-Mendez, A., Montes, R., Ambrose, L. R., Warrens, A. N., Laffan, M. and Lane, D. A. (2007). Proteolysis of the endothelial cell protein C receptor by neutrophil proteinase 3. J Thromb Haemost 5(5): 980-988.
  11. Preston, R. J., Villegas-Mendez, A., Sun, Y. H., Hermida, J., Simioni, P., Philippou, H., Dahlback, B. and Lane, D. A. (2005). Selective modulation of protein C affinity for EPCR and phospholipids by Gla domain mutation. FEBS J 272(1): 97-108.
1 Protocol published
Intracellular Staining for Phosphorylated STAT4 and STAT5 in Mouse Splenocytes
The Stat (Signal Transducer and Activator of Transcription) family of proteins are critical signal transducers involved in fundamental cellular processes, including cell growth and differentiation, development, apoptosis, immune responses and ...