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Coauthors
Kazuyoshi Ikuta Department of Virology, Research Institute for Microbial Diseases, Osaka University, Japan
3 protocols

Reviewer
Mayo Yasugi
  • Osaka Prefecture University
Research focus
  • Microbiology
Contributions
  • 2 Author merit
  • 3 Reviewer merit

Education

Ph.D. in Medical Science, Osaka University, 2010

Current Position

Assistant Professor in Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Izumisano, Osaka, Japan

Publications

  1. Yasugi, M., Kubota-Koketsu, R., Yamashita, A., Kawashita, N., Du, A., Misaki, R., Kuhara, M., Boonsathorn, N., Fujiyama, K., Okuno, Y., Nakaya, T. and Ikuta, K. (2013). Emerging antigenic variants at the antigenic site Sb in pandemic A(H1N1)2009 influenza virus in Japan detected by a human monoclonal antibody. PLoS One 8(10): e77892.
  2. Yasugi, M., Kubota-Koketsu, R., Yamashita, A., Kawashita, N., Du, A., Sasaki, T., Nishimura, M., Misaki, R., Kuhara, M., Boonsathorn, N., Fujiyama, K., Okuno, Y., Nakaya, T. and Ikuta, K. (2013). Human monoclonal antibodies broadly neutralizing against influenza B virus. PLoS Pathog 9(2): e1003150.
  3. Ramadhany, R., Yasugi, M., Nakamura, S., Daidoji, T., Watanabe, Y., Takahashi, K., Ikuta, K. and Nakaya, T. (2012). Tropism of Pandemic 2009 H1N1 Influenza a Virus. Front Microbiol 3: 128.
  4. Yasugi, M., Nakamura, S., Daidoji, T., Kawashita, N., Ramadhany, R., Yang, C. S., Yasunaga, T., Iida, T., Horii, T., Ikuta, K., Takahashi, K. and Nakaya, T. (2012). Frequency of D222G and Q223R hemagglutinin mutants of pandemic (H1N1) 2009 influenza virus in Japan between 2009 and 2010. PLoS One 7(2): e30946.
  5. Ueda, M., Daidoji, T., Du, A., Yang, C. S., Ibrahim, M. S., Ikuta, K. and Nakaya, T. (2010). Highly pathogenic H5N1 avian influenza virus induces extracellular Ca2+ influx, leading to apoptosis in avian cells. J Virol 84(6): 3068-3078.
  6. Nakamura, S., Yang, C. S., Sakon, N., Ueda, M., Tougan, T., Yamashita, A., Goto, N., Takahashi, K., Yasunaga, T., Ikuta, K., Mizutani, T., Okamoto, Y., Tagami, M., Morita, R., Maeda, N., Kawai, J., Hayashizaki, Y., Nagai, Y., Horii, T., Iida, T. and Nakaya, T. (2009). Direct metagenomic detection of viral pathogens in nasal and fecal specimens using an unbiased high-throughput sequencing approach. PLoS One 4(1): e4219.
  7. Du, A., Daidoji, T., Koma, T., Ibrahim, M. S., Nakamura, S., de Silva, U. C., Ueda, M., Yang, C. S., Yasunaga, T., Ikuta, K. and Nakaya, T. (2009). Detection of circulating Asian H5N1 viruses by a newly established monoclonal antibody. Biochem Biophys Res Commun 378(2): 197-202.
  8. Daidoji, T., Koma, T., Du, A., Yang, C. S., Ueda, M., Ikuta, K. and Nakaya, T. (2008). H5N1 avian influenza virus induces apoptotic cell death in mammalian airway epithelial cells. J Virol 82(22): 11294-11307.
  9. Ueda, M., Yamate, M., Du, A., Daidoji, T., Okuno, Y., Ikuta, K. and Nakaya, T. (2008). Maturation efficiency of viral glycoproteins in the ER impacts the production of influenza A virus. Virus Res 136(1-2): 91-97.
2 Protocols published
Isolation of Neutralizing Antibody
Authors:  Mayo Yasugi and Kazuyoshi Ikuta, date: 12/20/2013, view: 3515, Q&A: 0
Use of monoclonal antibodies (MAbs) is an established laboratory strategy for characterization of specific pathogens and their antigenicity. Especially, Human MAbs (HuMAbs) with neutralizing activity against specific virus could have potential ...
Influenza Virus-cell Fusion Inhibition Assay
Authors:  Mayo Yasugi and Kazuyoshi Ikuta, date: 12/20/2013, view: 4128, Q&A: 0
During viral infection to host cells, several viruses undergo the process of endocytosis and pH-dependent fusion. By fusion of viral membrane with host cellular membrane, the viral core invades to host cytoplasm. A part of monoclonal antibodies ...