Search
Coauthors
Kun‐Liang Guan Department of Pharmacology , University of California San Diego, La Jolla
2 protocols

Qun-Ying Lei Department of Biochemistry and Molecular Biology, Fudan University, China
1 protocol

Yue Xiong Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, USA
1 protocol

Di Zhao
  • Department of Biochemistry and Molecular Biology, Fudan University Shanghai Medical College, China
Contributions
  • 1 Author merit

Education

Ph.D. in Biochemistry and Molecular Biology, Institute of Biomedical Science, University of Fudan (expected in 2014)

Current position

Graduate student in Biochemistry and Molecular Biology, Institute of Biomedical Science, University of Fudan, China

Publications

  1. Zhao, D., Zou, S. W., Liu, Y., Zhou, X., Mo, Y., Wang, P., Xu, Y. H., Dong, B., Xiong, Y., Lei, Q. Y. and Guan, K. L. (2013). Lysine-5 acetylation negatively regulates lactate dehydrogenase A and is decreased in pancreatic cancer. Cancer Cell 23(4): 464-476.
  2. Lv, L., Li, D., Zhao, D., Lin, R., Chu, Y., Zhang, H., Zha, Z., Liu, Y., Li, Z., Xu, Y., Wang, G., Huang, Y., Xiong, Y., Guan, K. L. and Lei, Q. Y. (2011). Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth. Mol Cell 42(6): 719-730.
  3. Zhao, D., Xiong, Y., Lei, Q. Y. and Guan, K. L. (2013). LDH-A acetylation: implication in cancer. Oncotarget 4(6): 802-803.
1 Protocol published
LDH-A Enzyme Assay
Authors:  Di Zhao, Yue Xiong, Qun-Ying Lei and Kun-Liang Guan, date: 10/05/2013, view: 5076, Q&A: 0
LDH (Lactate dehydrogenase) enzyme catalyzes the reversible conversion of pyruvate to lactate using NAD+ as a cofactor. Although the physiological significance of lactate accumulation in tumor cells, a dead-end product in cellular metabolism, is ...