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Coauthors
Haixia Zhang Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, China
1 protocol

Yan Zhang
  • Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, China
Contributions
  • 1 Author merit

Education

Ph.D., School of Dentistry, Hiroshima University, Japan, 2000

Current position

Group Leader, Professor, Cancer and Stem Cell Biology, School of Life Sciences, Sun Yat-sen University, Guangzhou Higher Education Mega Center, P. R. China; Sun Yat-sen University-Griffith University Joint Laboratory for Drug Discovery

Director, Biomedical Center, Institute of Dongguan Sun Yat-sen University, P. R. China

Selected Publications (since 2011)

  1. Zhang, H., Wu, H., Zheng, J., Yu, P., Xu, L., Jiang, P., Gao, J., Wang, H. and Zhang, Y.* (2013). Transforming growth factor beta1 signal is crucial for dedifferentiation of cancer cells to cancer stem cells in osteosarcoma. Stem Cells 31(3): 433-446.
  2. Yang, T., Fang, S., Zhang, H. X., Xu, L. X., Zhang, Z. Q., Yuan, K. T., Xue, C. L., Yu, H. L., Zhang, S., Li, Y. F., Shi, H. P. and Zhang, Y.* (2013). N-3 PUFAs have antiproliferative and apoptotic effects on human colorectal cancer stem-like cells in vitro. J Nutr Biochem 24(5): 744-753.
  3. Shi, X., Zhang, Y., Zheng, J. and Pan, J.* (2012). Reactive oxygen species in cancer stem cells. Antioxid Redox Signal 16(11): 1215-1228.
  4. Zeng, T., Gao, H., Yu, P., He, H., Ouyang, X., Deng, L. and Zhang, Y.* (2011). Up-regulation of kin17 is essential for proliferation of breast cancer. PLoS One 6(9): e25343.
  5. Zhu, Y., Yu, F., Jiao, Y., Feng, J., Tang, W., Yao, H., Gong, C., Chen, J., Su, F., Zhang, Y.* and Song, E. (2011). Reduced miR-128 in breast tumor-initiating cells induces chemotherapeutic resistance via Bmi-1 and ABCC5. Clin Cancer Res 17(22): 7105-7115.
  6. Sun, D., Wang, X., Zhang, H., Deng, L. and Zhang, Y.* (2011). MMP9 mediates MICA shedding in human osteosarcomas. Cell Biol Int 35(6): 569-574.
    *Coresponding author

Book Chapter

  1. Zheng, J. and Zhang.Y. (2012). The microenvironment of cancer stem cell. Nutrition for Cancer. Beijing: People's Medical Publishing House. August, Chaper 5.
1 Protocol published
Chemosensitivity Assay
Authors:  Haixia Zhang and Yan Zhang, date: 09/05/2013, view: 4220, Q&A: 0
Chemoresistance is one of the special properties of cancer stem cells, which is the main cause of chemotherapy failure and plays an important role in the recurrence of various cancers including osteosarcoma. The most widely used assay for evaluating ...