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Coauthors
Andrea Tenner Molecular Biology and Biochemistry Department, University of California, USA
2 protocols

Marie Benoit Molecular Biology and Biochemistry Department, University of California, USA
2 protocols
Coreviewers
Alka Mehra Institute of Genomics and Integrative Biology
14 protocols

Guillaume Bompard Institut de Génétique Humaine
2 protocols

HongLok Lung University of Hong Kong
56 protocols

Jia Li SRI International
37 protocols

Reviewer
Elizabeth V. Clarke
  • Research associate, Kaiser Permanente
Research focus
  • Immunology
  • Genetic Epidemiology, Biobanking, Cancer, Preventative Medicine
Contributions
  • 2 Author merit
  • 5 Reviewer merit

Education

Ph.D., University of California Irvine, 2014

Publications

Analysis of the Putative Role of CR1 in Alzheimer's Disease: Genetic Association, Expression and Function.
Fonseca MI, Chu S, Pierce AL, Brubaker WD, Hauhart RE, Mastroeni D, Clarke EV, Rogers J, Atkinson JP, Tenner AJ.
PLoS One. 2016 Feb 25;11(2):e0149792. doi: 10.1371/journal.pone.0149792. eCollection 2016.

Complement protein C1q bound to apoptotic cells suppresses human macrophage and dendritic cell-mediated Th17 and Th1 T cell subset proliferation.
Clarke EV, Weist BM, Walsh CM, Tenner AJ.
J Leukoc Biol. 2015 Jan;97(1):147-60. doi: 10.1189/jlb.3A0614-278R. Epub 2014 Nov 7.

Complement modulation of T cell immune responses during homeostasis and disease.
Clarke EV, Tenner AJ.
J Leukoc Biol. 2014 Nov;96(5):745-56. doi: 10.1189/jlb.3MR0214-109R. Epub 2014 Sep 10. Review.

Purification of Human Monocytes and Lymphocyte Populations by Counter Current Elutriation- A Short Protocol.
Clarke EV, Benoit ME, Tenner AJ.
Bio Protoc. 2013 Dec 5;3(23). pii: e981.

Real-time imaging of Toxoplasma-infected human monocytes under fluidic shear stress reveals rapid translocation of intracellular parasites across endothelial barriers.
Ueno N, Harker KS, Clarke EV, McWhorter FY, Liu WF, Tenner AJ, Lodoen MB.
Cell Microbiol. 2014 Apr;16(4):580-95. doi: 10.1111/cmi.12239. Epub 2013 Dec 4.

C1q Binding to and Uptake of Apoptotic Lymphocytes by Human Monocyte-derived Macrophages.
Benoit ME, Clarke EV, Tenner AJ.
Bio Protoc. 2013 Sep 5;3(17). pii: e877.

Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells.
Benoit ME, Clarke EV, Morgado P, Fraser DA, Tenner AJ.
J Immunol. 2012 Jun 1;188(11):5682-93. doi: 10.4049/jimmunol.1103760. Epub 2012 Apr 20.

2 Protocols published
Purification of Human Monocytes and Lymphocyte Populations by Counter Current Elutriation – A Short Protocol
Authors:  Elizabeth V. Clarke, Marie E. Benoit and Andrea J. Tenner, date: 12/05/2013, view: 4585, Q&A: 0
Investigations of the activation processes involved in human monocytes and monocyte-derived macrophages and dendritic cells often required large numbers of cells that have not been possibly altered or activated by adherence to surfaces, by binding ...
C1q Binding to and Uptake of Apoptotic Lymphocytes by Human Monocyte-derived Macrophages
Authors:  Marie E. Benoit, Elizabeth V. Clarke and Andrea J. Tenner, date: 09/05/2013, view: 3756, Q&A: 0
To characterize macrophage gene expression profiles during the uptake of autologous apoptotic cells, we developed a unique, more physiologic system using primary human monocyte derived macrophages purified via a nonactivating isolation procedure ...
5 Protocols reviewed
Quantification of Tumor Material Uptake
Authors:  Richard N. Hanna and Catherine C. Hedrick, date: 10/20/2016, view: 2199, Q&A: 0
Extracellular tumor material including exosomes, microvesicles and apoptotic tumor debris may help cancers invade new organs. Enhancing the removal of extracellular tumor material by immune cells represents a novel immunotherapy approach for ...
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In vivo Imaging of Tumor and Immune Cell Interactions in the Lung
Authors:  Richard N. Hanna, Grzegorz Chodaczek and Catherine C. Hedrick, date: 10/20/2016, view: 1974, Q&A: 0
Immunotherapy has demonstrated great therapeutic potential by activating the immune system to fight cancer. However, little is known about the specific dynamics of interactions that occur between tumor and immune cells. In this protocol we describe ...
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