Search
Coauthors
Steven Ziegler Immunology Program, Benaroya Research Institute, USA
1 protocol
Coreviewers
Fanglian He University of Pennsylvania
205 protocols

Ivan Zanoni Harvard Medical School
64 protocols

Reviewer
Hongwei Han
  • Sanofi
Research focus
  • Immunology
  • 1 Author merit

Education

Ph.D. in Immunology, Institute for Enzyme Research, University of Tokushima, Japan, 2007

Current position

Staff Scientist, Benaroya Research Institute

Affiliate Instructor, University of Washington

Publications

  1. Ziegler, S. F., Roan, F., Bell, B. D., Stoklasek, T. A., Kitajima, M. and Han, H. (2013). The biology of thymic stromal lymphopoietin (TSLP). Adv Pharmacol 66: 129-155.
  2. Han, H., Headley, M. B., Xu, W., Comeau, M. R., Zhou, B. and Ziegler, S. F. (2013). Thymic stromal lymphopoietin amplifies the differentiation of alternatively activated macrophages. J Immunol 190(3): 904-912.
  3. Han, H., Xu, W., Headley, M. B., Jessup, H. K., Lee, K. S., Omori, M., Comeau, M. R., Marshak-Rothstein, A. and Ziegler, S. F. (2012). Thymic stromal lymphopoietin (TSLP)-mediated dermal inflammation aggravates experimental asthma. Mucosal Immunol 5(3): 342-351.
  4. Roan, F.§, Bell, B. D.§, Stoklasek, T. A.§, Kitajima, M.§, Han, H.§ and Ziegler, S. F. (2012). The multiple facets of thymic stromal lymphopoietin (TSLP) during allergic inflammation and beyond. J Leukoc Biol 91(6): 877-886. (§, co-1st author)
  5. Yano, M., Kuroda, N., Han, H., Meguro-Horike, M., Nishikawa, Y., Kiyonari, H., Maemura, K., Yanagawa, Y., Obata, K., Takahashi, S., Ikawa, T., Satoh, R., Kawamoto, H., Mouri, Y. and Matsumoto, M. (2008). Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance. J Exp Med 205(12): 2827-2838.
  6. Han, H. (2007). Target-organ specificity of autoimmunity is modified by thymic stroma and bone marrow-derived cells. J Med Invest 54(1-2): 54-64.
  7. Kinoshita, D., Hirota, F., Kaisho, T., Kasai, M., Izumi, K., Bando, Y., Mouri, Y., Matsushima, A., Niki, S., Han, H., Oshikawa, K., Kuroda, N., Maegawa, M., Irahara, M., Takeda, K., Akira, S. and Matsumoto, M. (2006). Essential role of IkappaB kinase alpha in thymic organogenesis required for the establishment of self-tolerance. J Immunol 176(7): 3995-4002.
  8. Niki, S., Oshikawa, K., Mouri, Y., Hirota, F., Matsushima, A., Yano, M., Han, H., Bando, Y., Izumi, K., Matsumoto, M., Nakayama, K. I. and Kuroda, N. (2006). Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice. J Clin Invest 116(5): 1292-1301.
  9. Kuroda, N., Mitani, T., Takeda, N., Ishimaru, N., Arakaki, R., Hayashi, Y., Bando, Y., Izumi, K., Takahashi, T., Nomura, T., Sakaguchi, S., Ueno, T., Takahama, Y., Uchida, D., Sun, S., Kajiura, F., Mouri, Y., Han, H., Matsushima, A., Yamada, G. and Matsumoto, M. (2005). Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice. J Immunol 174(4): 1862-1870.
  10. Uchida, D., Hatakeyama, S., Matsushima, A., Han, H., Ishido, S., Hotta, H., Kudoh, J., Shimizu, N., Doucas, V., Nakayama, K. I., Kuroda, N. and Matsumoto, M. (2004). AIRE functions as an E3 ubiquitin ligase. J Exp Med 199(2): 167-172.
  11. Kajiura, F., Sun, S., Nomura, T., Izumi, K., Ueno, T., Bando, Y., Kuroda, N., Han, H., Li, Y., Matsushima, A., Takahama, Y., Sakaguchi, S., Mitani, T. and Matsumoto, M. (2004). NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner. J Immunol 172(4): 2067-2075.
1 Protocol published
Bronchoalveolar Lavage and Lung Tissue Digestion
Authors:  Hongwei Han and Steven F. Ziegler, date: 08/20/2013, view: 16630, Q&A: 0
Bronchoalveolar lavage (BAL) is a simple but valuable and typically performed technique commonly used for studying the pathogenesis of lung diseases such as asthma and COPD. Cell counts can be combined with new methods for examining inflammatory ...
3 Protocols reviewed
Isolation of Highly Pure Primary Mouse Alveolar Epithelial Type II Cells by Flow Cytometric Cell Sorting
Authors:  Meenal Sinha and Clifford A. Lowell, date: 11/20/2016, view: 4026, Q&A: 0
In this protocol, we describe the method for isolating highly pure primary alveolar epithelial type II (ATII) cells from lungs of naïve mice. The method combines negative selection for a variety of lineage markers along with positive selection for ...
More >
Dye Labeling of Live Nippostrongylus brasiliensis Larvae for Visualization in Host Tissue
Authors:  Tiffany Bouchery, Mali Camberis and Graham Le Gros, date: 02/20/2016, view: 2394, Q&A: 0
Visualization of the interaction between parasitic nematodes and their host enables a better understanding of the development of the nematode during the infectious stages of its life cycle and of the effects of host response on nematode integrity in ...
More >