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Coauthors
Esteban Orellana Department of Biological Sciences, Bindley Bioscience Center, Purdue University, USA
1 protocol

Frank Slack Molecular, Cellular and Developmental Biology Department, Yale University, USA
1 protocol

Andrea L. Kasinski
  • Department of Biological Sciences, Bindley Bioscience Center, Purdue University, USA
Contributions
  • 2 Author merit

Education

Ph.D. in Genetics and Molecular Biology, Emory University, 2009

Current position

William and Patty Miller Assistant Professor of Biological Sciences, Purdue University

Publications

Peer Reviewed Journals Articles

  1. *Kasinski, A.L. and Slack, F.J. (2013). Generation of mouse lung epithelial cells. Bio-protocols.org, 3(15):http://www.bio-protocol.org/wenzhang.aspx?id=837 (Invited submission). * corresponding author
  2. Puckett, M. C., Goldman, E. H., Cockrell, L. M., Huang, B., Kasinski, A. L., Du, Y., Wang, C. Y., Lin, A., Ichijo, H., Khuri, F. and Fu, H. (2013). Integration of apoptosis signal-regulating kinase 1-mediated stress signaling with the Akt/protein kinase B-IkappaB kinase cascade. Mol Cell Biol 33(11): 2252-2259.
  3. Kasinski, A. L. and Slack, F. J. (2012). miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma. Cancer Res 72(21): 5576-5587.
  4. Kasinski, A. L. and Slack, F. J. (2012). Arresting the Culprit: Targeted Antagomir Delivery to Sequester Oncogenic miR-221 in HCC. Mol Ther Nucleic Acids 1: e12..
  5. Kasinski, A. L. and Slack, F. J. (2011). Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy. Nat Rev Cancer 11(12): 849-864.
  6. Kim, M., Kasinski, A. L. and Slack, F. J. (2011). MicroRNA therapeutics in preclinical cancer models. Lancet Oncol 12(4): 319-321.
  7. Kasinski, A.L., Fu, H. (2011) 14-3-3 zeta. UCSD-Nature Molecule Pages. (doi:10.1038/mp.a000060.01)
  8. Kasinski, A. L. and Slack, F. J. (2010). Potential microRNA therapies targeting Ras, NFkappaB and p53 signaling. Curr Opin Mol Ther 12(2): 147-157.
  9. Kasinski, A. L., Du, Y., Thomas, S. L., Zhao, J., Sun, S. Y., Khuri, F. R., Wang, C. Y., Shoji, M., Sun, A., Snyder, J. P., Liotta, D. and Fu, H. (2008). Inhibition of IkappaB kinase-nuclear factor-kappaB signaling pathway by 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24), a novel monoketone analog of curcumin. Mol Pharmacol 74(3): 654-661.
  10. Kasinski, A., Doering, C. B. and Danner, D. J. (2004). Leucine toxicity in a neuronal cell model with inhibited branched chain amino acid catabolism. Brain Res Mol Brain Res 122(2): 180-187.
  11. Nellis, M. M., Kasinski, A., Carlson, M., Allen, R., Schaefer, A. M., Schwartz, E. M. and Danner, D. J. (2003). Relationship of causative genetic mutations in maple syrup urine disease with their clinical expression. Mol Genet Metab 80(1-2): 189-195.
  12. Nellis, M. M., Doering, C. B., Kasinski, A. and Danner, D. J. (2002). Insulin increases branched-chain alpha-ketoacid dehydrogenase kinase expression in Clone 9 rat cells. Am J Physiol Endocrinol Metab 283(4): E853-860.

Peer-reviewed Books and Chapters

  1. Park, H.R., Cockrell, L.M., Du, Y., Kasinski, A., Havel, J., Zhao, J., Reyes-Turcu, F., Wilkinson, K., Fu, H. (2008). Methods for Protein-Protein Interactions, Molecular Biomethods Handbook 2nd Edition.
  2. Danner, D.J., Muller, E.A., Kasinski, A. (2003). The complexity of single gene disorders: Lessons from maple syrup urine disease and thiamin responsiveness. Thiamine: catalytic mechanisms and role in normal and disease states. Ed by M.S. Patel and F. Jordan, Academic Press (2004).
2 Protocols published
Sulforhodamine B (SRB) Assay in Cell Culture to Investigate Cell Proliferation
Authors:  Esteban A. Orellana and Andrea L. Kasinski, date: 11/05/2016, view: 5800, Q&A: 0
The SRB assay has been used since its development in 1990 (Skehan et al., 1990) to inexpensively conduct various screening assays to investigate cytotoxicity in cell based studies (Vichai and Kirtikara, 2006). This method relies on the ...
Generation of Mouse Lung Epithelial Cells
Authors:  Andrea L. Kasinski and Frank J. Slack, date: 08/05/2013, view: 4686, Q&A: 0
Although in vivo models are excellent for assessing various facets of whole organism physiology, pathology, and overall response to treatments, evaluating basic cellular functions, and molecular events in mammalian model systems is ...