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Coauthors
Ana Traven Department of Biochemistry and Molecular Biology, Monash University, Australia
2 protocols

Victoria Hewitt Department of Biochemistry and Molecular Biology and Department of Microbiology, Monash University, Australia
2 protocols

Trevor Lithgow
  • Department of Biochemistry and Molecular Biology and Department of Microbiology, Monash University, Australia
Contributions
  • 2 Author merit

Education

Ph.D. in Biochemistry, La Trobe University in Melbourne, 1992

Current position

Trevor Lithgow is a Professor in the School of Biomedical Sciences at Monash University and a Fellow of the Australian Academy of Sciences. Professor Lithgow’s lab has expertise in molecular biology, cell biology, microbiology and bioinformatics. Current research projects in the Lithgow lab include the discovery and characterization of protein transport machines in bacteria and mitochondria, understanding the assembly of these and other molecular machines on bacterial cell surfaces, and studying the evolution of bacterial cell surfaces

Publications

  1. Dunstan, R. A., Heinz, E., Wijeyewickrema, L. C., Pike, R. N., Purcell, A. W., Evans, T. J., Praszkier, J., Robins-Browne, R. M., Strugnell, R. A., Korotkov, K. V. and Lithgow, T. (2013). Assembly of the type II secretion system such as found in Vibrio cholerae depends on the novel Pilotin AspS. PLoS Pathog 9(1): e1003117.
  2. Hewitt, V. L., Heinz, E., Shingu-Vazquez, M., Qu, Y., Jelicic, B., Lo, T. L., Beilharz, T. H., Dumsday, G., Gabriel, K., Traven, A. and Lithgow, T. (2012). A model system for mitochondrial biogenesis reveals evolutionary rewiring of protein import and membrane assembly pathways. Proc Natl Acad Sci U S A 109(49): E3358-3366.
  3. Selkrig, J., Mosbahi, K., Webb, C. T., Belousoff, M. J., Perry, A. J., Wells, T. J., Morris, F., Leyton, D. L., Totsika, M., Phan, M. D., Celik, N., Kelly, M., Oates, C., Hartland, E. L., Robins-Browne, R. M., Ramarathinam, S. H., Purcell, A. W., Schembri, M. A., Strugnell, R. A., Henderson, I. R., Walker, D. and Lithgow, T. (2012). Discovery of an archetypal protein transport system in bacterial outer membranes. Nat Struct Mol Biol 19(5): 506-510, S501.
  4. Webb, C. T., Heinz, E. and Lithgow, T. (2012). Evolution of the beta-barrel assembly machinery. Trends Microbiol 20(12): 612-620.
2 Protocols published
Candida albicans Mitochondrial Protein Import Assay
Authors:  Victoria L Hewitt, Trevor Lithgow and Ana Traven, date: 02/20/2013, view: 4204, Q&A: 0
We have established the use of Candida albicans as a new model system to study mitochondrial biogenesis. This dimorphic yeast provides an excellent system to investigate the coordination of mitochondrial biogenesis with other cellular ...
Preparation of Mitochondria from Candida albicans
Authors:  Victoria L Hewitt, Trevor Lithgow and Ana Traven, date: 02/20/2013, view: 4377, Q&A: 0
Based on the methods of (Daum et al., 1982) and (Hewitt et al., 2012), we have established the use of Candida albicans as a new model system to study mitochondrial biogenesis. This dimorphic yeast provides an excellent ...