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Christian Behrends
  • Munich Cluster for Systems Neurology (SyNergy), Ludwig-Maximilians-University Munich
Contributions
  • 1 Author merit

Education

Dr. rer. nat, Ludwig-Maximilians-Universität München, Germany

Current position

Prof., Munich Cluster of Systems Neurology (SyNergy), Ludwig-Maximilians-Universität München, Germany

Publications (selected)

  1. Polajnar, M., Dietz, M. S., Heilemann, M. and Behrends, C. (2017). Expanding the host cell ubiquitylation machinery targeting cytosolic Salmonella. EMBO Rep.
  2. Jung, J., Nayak, A., Schaeffer, V., Starzetz, T., Kirsch, A. K., Muller, S., Dikic, I., Mittelbronn, M. and Behrends, C. (2017). Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. Elife 6.
  3. Reiterer, V., Figueras-Puig, C., Le Guerroue, F., Confalonieri, S., Vecchi, M., Jalapothu, D., Kanse, S. M., Deshaies, R. J., Di Fiore, P. P., Behrends, C. and Farhan, H. (2017). The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function. EMBO J 36(3): 260-273.
  4. Fiskin, E., Bionda, T., Dikic, I. and Behrends, C. (2016). Global Analysis of Host and Bacterial Ubiquitinome in Response to Salmonella Typhimurium Infection. Mol Cell 62(6): 967-981.
  5. Lamb, C. A., Nuhlen, S., Judith, D., Frith, D., Snijders, A. P., Behrends, C. and Tooze, S. A. (2016). TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic. EMBO J 35(3): 281-301.
  6. Stadel, D., Millarte, V., Tillmann, K. D., Huber, J., Tamin-Yecheskel, B. C., Akutsu, M., Demishtein, A., Ben-Zeev, B., Anikster, Y., Perez, F., Dotsch, V., Elazar, Z., Rogov, V., Farhan, H. and Behrends, C. (2015). TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export. Mol Cell 60(1): 89-104.
  7. Jung, J., Genau, H. M. and Behrends, C. (2015). Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9. Molecular and Cellular Biology 35: 2479-94.
  8. Genau, H. M., Huber, J., Baschieri, F., Akutsu, M., Dotsch, V., Farhan, H., Rogov, V. and Behrends, C. (2015). CUL3-KBTBD6/KBTBD7 ubiquitin ligase cooperates with GABARAP proteins to spatially restrict TIAM1-RAC1 signaling. Mol Cell 57(6): 995-1010.
  9. Popovic, D., Akutsu, M., Novak, I., Harper, J. W., Behrends, C. and Dikic, I. (2012). Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers. Mol Cell Biol 32(9): 1733-1744.
  10. Behrends, C., Sowa, M. E., Gygi, S. P. and Harper, J. W. (2010). Network organization of the human autophagy system. Nature 466(7302): 68-76.
1 Protocol published
Protocol for Establishing a Multiplex Image-based Autophagy RNAi Screen in Cell Cultures
Authors:  Jennifer Jung and Christian Behrends, date: 09/05/2017, view: 225, Q&A: 0
Autophagy is a recycling pathway, in which intracellular cargoes including protein aggregates and bacteria are engulfed by autophagosomes and subsequently degraded after fusion with lysosomes. Dysregulation of this process is involved in several ...