Education
M.Sc. in Epidemiology and Biostatistics, McGill University, 2004
M.D.CM, Faculty of Medicine, McGill University, Montreal, 1997
Current position
Assistant professor, Department of Medicine, Faculty of Medicine, McGill University
Associate member, Departments of Microbiology and Immunology, and Experimental Medicine
Full-time clinical staff, Division of Respirology, McGill University Health Center
Publications
-
Beaudoin, T., LaFayette, S., Roussel, L., Bérubé, J., Desrosiers, M., Nguyen, D. and Rousseau, S. (2013). The level of p38α MAPK activation in airway epithelial cells determines the onset of innate immune responses to planktonic and biofilm Pseudomonas aeruginosa. Journal of Infectious Diseases.
-
Khakimova, M., Ahlgren, H. G., Harrison, J. J., English, A. M. and Nguyen, D. (2013). The Stringent Response Controls Catalases in Pseudomonas aeruginosa and Is Required for Hydrogen Peroxide and Antibiotic Tolerance. J Bacteriol 195(9): 2011-2020.
-
Beaudoin, T., LaFayette, S., Nguyen, D. and Rousseau, S. (2012). Mucoid Pseudomonas aeruginosa caused by mucA mutations result in activation of TLR2 in addition to TLR5 in airway epithelial cells. Biochem Biophys Res Commun. 428(1):150-4.
-
Nguyen, D.*, Joshi-Datar, A., Lepine, F., Bauerle, E., Olakanmi, O., Beer, K., McKay, G., Siehnel, R., Schafhauser, J. and Wang, Y. (2011). Active starvation responses mediate antibiotic tolerance in biofilms and nutrient-limited bacteria. Science 334(6058): 982-986. *Corresponding author
Recommended in Faculty of 1000 as a “must read” publication.
Featured in Scientific American Health News http://www.scientificamerican.com/article.cfm?id=antibiotic-tolerance
Highlighted in Nature Microbiology reviews http://www.nature.com/nrmicro/journal/v10/n1/full/nrmicro2721.html
-
Pepperell, C. S., Granka, J. M., Alexander, D. C., Behr, M. A., Chui, L., Gordon, J., Guthrie, J. L., Jamieson, F. B., Langlois-Klassen, D., Long, R., Nguyen, D., Wobeser, W. and Feldman, M. W. (2011). Dispersal of Mycobacterium tuberculosis via the Canadian fur trade. Proc Natl Acad Sci U S A 108(16): 6526-6531.
-
Nguyen, D., Emond, M. J., Mayer‐Hamblett, N., Saiman, L., Marshall, B. C. and Burns, J. L. (2007). Clinical response to azithromycin in cystic fibrosis correlates with in vitro effects on Pseudomonas aeruginosa phenotypes. Pediatric pulmonology 42(6): 533-541.
-
Nguyen, D. and Singh, P. K. (2006). Evolving stealth: genetic adaptation of Pseudomonas aeruginosa during cystic fibrosis infections. Proceedings of the National Academy of Sciences 103(22): 8305-8306.