Education
Ph.D. in Institute of Neuroscience and Physiology, University of Gothenburg, Sweden, 2004
Current position
Associate Professor, Institute of Neuroscience and Physiology, University of Gothenburg, Sweden (2013–present)
Publications (since 2010)
-
Bi, D., Qiao, L., Bergelson, I., Ek, C. J., Duan, L., Zhang, X., Albertsson, A. M., Pettengill, M., Kronforst, K., Ninkovic, J., Goldmann, D., Janzon, A., Hagberg, H., Wang, X.*, Mallard, C.* and Levy, O.* (2015). Staphylococcus epidermidis bacteremia induces brain injury in neonatal mice via toll-like receptor 2-dependent and -independent pathways. J Infect Dis. (*Equal contribution senior authors; Wang X is the corresponding author)
-
Ali, A., Zhu, X., Kwiecinski, J., Gjertsson, I., Lindholm, C., Iwakura, Y., Wang, X., Lycke, N., Josefsson, E., Pullerits, R. and Jin, T. (2015). Antibiotic-killed Staphylococcus aureus induces destructive arthritis in mice. Arthritis Rheumatol 67(1): 107-116.
-
Albertsson, A. M., Bi, D., Duan, L., Zhang, X., Leavenworth, J. W., Qiao, L., Zhu, C., Cardell, S., Cantor, H., Hagberg, H., Mallard, C. and Wang, X. (2014). The immune response after hypoxia-ischemia in a mouse model of preterm brain injury. J Neuroinflammation 11: 153.
-
Albertsson, A. M., Zhang, X., Leavenworth, J., Bi, D., Nair, S., Qiao, L., Hagberg, H., Mallard, C., Cantor, H. and Wang, X. (2014). The effect of osteopontin and osteopontin-derived peptides on preterm brain injury. J Neuroinflammation 11: 197.
-
Bi, D., Chen, M., Zhang, X., Wang, H., Xia, L., Shang, Q., Li, T., Zhu, D., Blomgren, K., He, L., Wang, X., Xing, Q. and Zhu, C. (2014). The association between sex-related interleukin-6 gene polymorphisms and the risk for cerebral palsy. J Neuroinflammation 11: 100.
-
Xie, C., Zhou, K., Wang, X., Blomgren, K. and Zhu, C. (2014). Therapeutic benefits of delayed lithium administration in the neonatal rat after cerebral hypoxia-ischemia. PLoS One 9(9): e107192.
-
Han, W., Sun, Y., Wang, X., Zhu, C. and Blomgren, K. (2014). Delayed, long-term administration of the caspase inhibitor Q-VD-OPh reduced brain injury induced by neonatal hypoxia-ischemia. Dev Neurosci 36(1): 64-72.
-
Sun, H., Cheng, R., Kang, W., Xiong, H., Zhou, C., Zhang, Y., Wang, X. and Zhu, C. (2014). High-frequency oscillatory ventilation versus synchronized intermittent mandatory ventilation plus pressure support in preterm infants with severe respiratory distress syndrome. Respir Care 59(2): 159-169.
-
Leavenworth, J. W., Tang, X., Kim, H. J., Wang, X. and Cantor, H. (2013). Amelioration of arthritis through mobilization of peptide-specific CD8+ regulatory T cells. J Clin Invest 123(3): 1382-1389.
-
Stridh, L., Mottahedin, A., Johansson, M. E., Valdez, R. C., Northington, F., Wang, X. and Mallard, C. (2013). Toll-like receptor-3 activation increases the vulnerability of the neonatal brain to hypoxia-ischemia. J Neurosci 33(29): 12041-12051.
-
Correa, F., Ljunggren, E., Patil, J., Wang, X., Hagberg, H., Mallard, C. and Sandberg, M. (2013). Time-dependent effects of systemic lipopolysaccharide injection on regulators of antioxidant defence Nrf2 and PGC-1alpha in the neonatal rat brain. Neuroimmunomodulation 20(4): 185-193.
-
Stridh, L., Ek, C. J., Wang, X., Nilsson, H. and Mallard, C. (2013). Regulation of Toll-like receptors in the choroid plexus in the immature brain after systemic inflammatory stimuli. Transl Stroke Res 4(2): 220-227.
-
Zhu, C., Sun, Y., Gao, J., Wang, X., Plesnila, N. and Blomgren, K. (2013). Inhaled nitric oxide protects males but not females from neonatal mouse hypoxia-ischemia brain injury. Transl Stroke Res 4(2): 201-207.
-
Kronforst, K. D., Mancuso, C. J., Pettengill, M., Ninkovic, J., Power Coombs, M. R., Stevens, C., Otto, M., Mallard, C., Wang, X., Goldmann, D. and Levy, O. (2012). A neonatal model of intravenous Staphylococcus epidermidis infection in mice <24 h old enables characterization of early innate immune responses. PLoS One 7(9): e43897.
-
You, F., Huo, K., Wang, R., Xu, D., Deng, J., Wei, Y., Shi, F., Liu, H., Cheng, G., Zhang, Z., Yang, P., Sun, T., Wang, X., Jacobsson, B. and Zhu, C. (2012). Maternal mortality in Henan Province, China: changes between 1996 and 2009. PLoS One 7(10): e47153.
-
Huo, K., Sun, Y., Li, H., Du, X., Wang, X., Karlsson, N., Zhu, C. and Blomgren, K. (2012). Lithium reduced neural progenitor apoptosis in the hippocampus and ameliorated functional deficits after irradiation to the immature mouse brain. Mol Cell Neurosci 51(1-2): 32-42.
-
Carlsson, Y., Schwendimann, L., Vontell, R., Rousset, C. I., Wang, X., Lebon, S., Charriaut-Marlangue, C., Supramaniam, V., Hagberg, H., Gressens, P. and Jacotot, E. (2011). Genetic inhibition of caspase-2 reduces hypoxic-ischemic and excitotoxic neonatal brain injury. Ann Neurol 70(5): 781-789.
-
Sun, Y., Zhang, Y., Wang, X., Blomgren, K. and Zhu, C. (2012). Apoptosis-inducing factor downregulation increased neuronal progenitor, but not stem cell, survival in the neonatal hippocampus after cerebral hypoxia-ischemia. Mol Neurodegener 7: 17.
-
Leavenworth, J. W.*, Wang, X.*, Wenander, C. S., Spee, P. and Cantor, H. (2011). Mobilization of natural killer cells inhibits development of collagen-induced arthritis. Proc Natl Acad Sci U S A 108(35): 14584-14589. (*Wang X is an equally contributing first author)
-
Du, X., Fleiss, B., Li, H., D'Angelo, B., Sun, Y., Zhu, C., Hagberg, H., Levy, O., Mallard, C. and Wang, X. (2011). Systemic stimulation of TLR2 impairs neonatal mouse brain development. PLoS One 6(5): e19583.
-
Wang, X., Leverin, A. L., Han, W., Zhu, C., Johansson, B. R., Jacotot, E., Ten, V. S., Sims, N. R. and Hagberg, H. (2011). Isolation of brain mitochondria from neonatal mice. J Neurochem 119(6): 1253-1261.
-
Stridh, L., Smith, P. L., Naylor, A. S., Wang, X. and Mallard, C. (2011). Regulation of toll-like receptor 1 and -2 in neonatal mice brains after hypoxia-ischemia. J Neuroinflammation 8: 45.
-
Gressens, P., Le Verche, V., Fraser, M., Rousset, C. I., Schwendimann, L., Bennet, L., George, S. A., Wang, X., Mallard, C., Tilley, B. C., Dournaud, P., Gunn, A. J., Hagberg, H. and Levison, S. W. (2011). Pitfalls in the quest of neuroprotectants for the perinatal brain. Dev Neurosci 33(3-4): 189-198.
-
Chauvier, D., Renolleau, S., Holifanjaniaina, S., Ankri, S., Bezault, M., Schwendimann, L., Rousset, C., Casimir, R., Hoebeke, J., Smirnova, M., Debret, G., Trichet, A. P., Carlsson, Y., Wang, X., Bernard, E., Hebert, M., Rauzier, J. M., Matecki, S., Lacampagne, A., Rustin, P., Mariani, J., Hagberg, H., Gressens, P., Charriaut-Marlangue, C. and Jacotot, E. (2011). Targeting neonatal ischemic brain injury with a pentapeptide-based irreversible caspase inhibitor. Cell Death Dis 2: e203.
-
Li, H., Li, Q., Du, X., Sun, Y., Wang, X., Kroemer, G., Blomgren, K. and Zhu, C. (2011). Lithium-mediated long-term neuroprotection in neonatal rat hypoxia-ischemia is associated with antiinflammatory effects and enhanced proliferation and survival of neural stem/progenitor cells. J Cereb Blood Flow Metab 31(10): 2106-2115.
-
Carlsson, Y., Schwendimann, L., Vontell, R., Rousset, C. I., Wang, X., Lebon, S., Charriaut-Marlangue, C., Supramaniam, V., Hagberg, H., Gressens, P. and Jacotot, E. (2011). Genetic inhibition of caspase-2 reduces hypoxic-ischemic and excitotoxic neonatal brain injury. Ann Neurol 70(5): 781-789.
-
Hellgren, G., Han, W., Wang, X., Lofqvist, C., Hagberg, H., Mallard, C. and Hellstrom, A. (2011). Safety aspects of longitudinal administration of IGF-I/IGFBP-3 complex in neonatal mice. Growth Horm IGF Res 21(4): 205-211.
-
Gao, J., Wang, S., Wang, X. and Zhu, C. (2011). Electroacupuncture enhances cell proliferation and neuronal differentiation in young rat brains. Neurol Sci 32(3): 369-374.
-
Han, W., Song, J., Liu, A., Huo, K., Xu, F., Cui, S., Wang, X. and Zhu, C. (2011). Trends in live births in the past 20 years in Zhengzhou, China. Acta Obstet Gynecol Scand 90(4): 332-337.
-
Huo, K., Zhang, Z., Zhao, D., Li, H., Wang, J., Wang, X., Feng, H., Wang, X. and Zhu, C. (2011). Risk factors for neurodevelopmental deficits in congenital hypothyroidism after early substitution treatment. Endocr J 58(5): 355-361.
-
Li, Q., Li, H., Roughton, K., Wang, X., Kroemer, G., Blomgren, K. and Zhu, C. (2010). Lithium reduces apoptosis and autophagy after neonatal hypoxia-ischemia. Cell Death Dis 1: e56.
-
Wang, X., Han, W., Du, X., Zhu, C., Carlsson, Y., Mallard, C., Jacotot, E. and Hagberg, H. (2010). Neuroprotective effect of Bax-inhibiting peptide on neonatal brain injury. Stroke 41(9): 2050-2055.
-
Huo, K., Zhao, Y., Feng, H., Yao, M., Savman, K., Wang, X. and Zhu, C. (2010). Mortality rates of children aged under five in Henan province, China, 2004-2008. Paediatr Perinat Epidemiol 24(4): 343-348.
-
Dean, J. M., Wang, X., Kaindl, A. M., Gressens, P., Fleiss, B., Hagberg, H. and Mallard, C. (2010). Microglial MyD88 signaling regulates acute neuronal toxicity of LPS-stimulated microglia in vitro. Brain Behav Immun 24(5): 776-783.