Education

Ph.D., University College London, 1973

Current position

Group leader MRC Laboratory of Molecular Biology, Cambridge (1984-present)

Publications (since 2006)

115 total (including 13 in Nature/Cell/Science) plus 19 more from my group; 1 patent

1. Bloomfield, G., Traynor, D., Sander, S. P., Veltman, D. M., Pachebat, J. A. and Kay, R. R. (2015). Neurofibromin controls macropinocytosis and phagocytosis in Dictyostelium. Elife 4.
   
2. Fets, L., Nichols, J. M. and Kay, R. R. (2014). A PIP5 kinase essential for efficient chemotactic signaling. Curr Biol 24(4): 415-421.
   
3. Zatulovskiy, E., Tyson, R., Bretschneider, T. and Kay, R. R. (2014). Bleb-driven chemotaxis of Dictyostelium cells. J Cell Biol 204(6): 1027-1044.
   
4. Clark, J.*, Kay, R. R.*, Kielkowska, A., Niewczas, I., Fets, L., Oxley, D., Stephens, L. R. and Hawkins, P. T. (2014). Dictyostelium uses ether-linked inositol phospholipids for intracellular signalling. EMBO J 33(19): 2188-2200. (*Co-first authors)
   
5. Hoeller, O., Bolourani, P., Clark, J., Stephens, L. R., Hawkins, P. T., Weiner, O. D., Weeks, G. and Kay, R. R. (2013). Two distinct functions for PI3-kinases in macropinocytosis. J Cell Sci 126(Pt 18): 4296-4307.
   
6. Wong, C. C., Traynor, D., Basse, N., Kay, R. R. and Warren, A. J. (2011). Defective ribosome assembly in Shwachman-Diamond syndrome. Blood 118(16): 4305-4312.
   
7. Velazquez, F., Peak-Chew, S. Y., Fernandez, I. S., Neumann, C. S. and Kay, R. R. (2011). Identification of a eukaryotic reductive dechlorinase and characterization of its mechanism of action on its natural substrate. Chem Biol 18(10): 1252-1260.
   
8. Neumann, C. S., Walsh, C. T. and Kay, R. R. (2010). A flavin-dependent halogenase catalyzes the chlorination step in the biosynthesis of Dictyostelium differentiation-inducing factor 1. Proc Natl Acad Sci U S A 107(13): 5798-5803.
   
9. Zanchi, R., Howard, G., Bretscher, M. S. and Kay, R. R. (2010). The exocytic gene secA is required for Dictyostelium cell motility and osmoregulation. J Cell Sci 123(Pt 19): 3226-3234.
   
10. Bloomfield, G., Skelton, J., Ivens, A., Tanaka, Y. and Kay, R. R. (2010). Sex determination in the social amoeba Dictyostelium discoideum. Science 330(6010): 1533-1536.
    
11. Bloomfield, G., Tanaka, Y., Skelton, J., Ivens, A. and Kay, R. R. (2008). Widespread duplications in the genomes of laboratory stocks of Dictyostelium discoideum. Genome Biol 9(4): R75.
    
12. Kay, R. R., Langridge, P., Traynor, D. and Hoeller, O. (2008). Changing directions in the study of chemotaxis. Nat Rev Mol Cell Biol 9(6): 455-463.
    
13. Hoeller, O. and Kay, R. R. (2007). Chemotaxis in the absence of PIP3 gradients. Curr Biol 17(9): 813-817.
    
14. Traynor, D. and Kay, R. R. (2007). Possible roles of the endocytic cycle in cell motility. J Cell Sci 120(Pt 14): 2318-2327.
    
15. Saito, T., Taylor, G. W., Yang, J. C., Neuhaus, D., Stetsenko, D., Kato, A. and Kay, R. R. (2006). Identification of new differentiation inducing factors from Dictyostelium discoideum. Biochim Biophys Acta 1760(5): 754-761.
    
16. Austin, M. B., Saito, T., Bowman, M. E., Haydock, S., Kato, A., Moore, B. S., Kay, R. R.* and Noel, J. P.* (2006). Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase. Nat Chem Biol 2(9): 494-502. (*Senior co-authors)